Page 154 - NPPA full book

Pharmacogenomics Research and

Personalized Medicine

Tailor-made dosing of medicines not only minimises
side-effects but is also efficient in terms of economics.
Use of genomic information during treatments and more
importantly, during drug discovery is pivotal for the full
realisation of pharmacogenomics.

Use of advanced

01 07 therapies like CAR
T-cell therapy
Gut Microbiota
Research

Has major implications
for medical therapy Antiviral
and drug development Antibacterial Drug
across multiple disease
indications. Similarly, the Discovery and
use of other microbiome NIPERs PLAYING Development
information, like the skin, 02 06
oral and vaginal will play PIVOTAL ROLE IN NIPER, Mohali, has proposed
a significant role in drug FUTURE R&D to set up a centre of excellence
discovery targeted to with an objective for affordable
these organs. screening approach for detection
of pathogenic organisms, and
development of vaccine against
multi drug resistant hospital
acquired bacterial/viral infection.

03 05

Biomarkers Research 04 Drug Repurposing
Curtails the total duration of
More research is required to substantiate development process and overall
use of personalised medicine using cost required for traditional drug
geography-specific population genomic data. Antimicrobial resistance discovery.
Improvement in accuracy of risk prediction
of a disease has enormous potential in (AMR)
management of lifestyle diseases that are on The lean drug discovery pipeline for
rampant rise.
antibiotics and development of AMR
presents multi-fold challenges and it would
require further focus and the strengthening
of epidemiological surveillance.

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